Antimicrobial Resistance Prediction using Game Theory Algorithm

The increasing prevalence of antibiotic-resistant bacteria is a growing problem around the world. Every year, millions of people are infected with drug-resistant pathogens, and a lot of people die from pneumonia or bloodstream infections.

In recent years, researchers have been working to make use of genome sequencing to identify antibiotic-resistant genes, looking for similar sequences of genes in public databases. This works for identifying well-known antibiotic-resistant genes, but doesn’t hold up with new or unusual genes.

Washington State University researchers have developed a novel way to identify previously unrecognized antibiotic-resistance genes in bacteria.

In their work, the WSU team decided to use game theory, a tool that is used in several fields, especially economics, to model strategic interactions between game players, to help identify antibiotic resistant genes. In game theory, models determine how the behavior of one participant affects and depends on the behavior of other players.

This novel game theory approach used to determine protein features for this machine learning algorithm has not been used previously for such a purpose and is especially powerful because features are chosen on the basis of how well they work together as a whole to identify putative antimicrobial-resistance genes by taking into account both the relevance and interdependency of features.

By employing machine learning and game theory, the researchers were able to determine with 93 to 99 percent accuracy the presence of antibiotic-resistant genes in three different types of Gram-negative bacteria.

References:






Top 10 Technology Trends in 2021

Technology is ever-evolving regardless of the current market conditions. New technologies are emerging with groundbreaking innovations to tackle world issues. It must be strange that predictions are being made about the future of technolog.......Read more...

Top 10 free open-source RSS feed readers for Linux desktops

The internet has problems, let's say there are 50 million weblogs, and it's going up, our focus here is on a new and efficient way to keep up with all the cool stuff that's happening on the Internet. What we are talking about is using a si.......Read more...

theClinicians: A Free Telemedicine Mobile App for clinicians in Saudi Arabia Gains a New Update

theClinicians is a mobile communication application for physicians. It's begin developed by Saudi Telecommunication Company (STC) to ease communication among medical specialists and consultants. The project started in 2016 and gain some p.......Read more...

Facebook Launches COVID-19 Information Support as a response to Coronavirus Pandemic

Facebook is the biggest social media network in the world, It has almost 2.5 billion active users per month as in the fourth quarter of 2019. It's widely used by users to stay connected with their family, friends and often work colleges. S.......Read more...

Switzerland initiated COVID-19 Science Task Force

Switzerland has its own Science task force as a response to COVID-19 pandemics. It is a required initiative to put all the scientific minds into good use to advise, plan and overcome the challenges for the threats. Source: Outbreaks monit.......Read more...